Discover how isoxanthohumol, a compound found in hops, may overcome chemotherapy drug resistance in cancer treatment through groundbreaking research.
Discover how proteomics reveals the molecular mechanisms behind cancer drug resistance by comparing protein expression in sensitive and resistant breast cancer cells.
Discover how SYK inhibition effectively overcomes MCL-1 mediated ABT-199 resistance in CLL cells compared to BTK or PI3Kδ inhibition.
Discover how targeting intracellular pH regulation offers a novel approach to overcome drug resistance in FLT3/ITD mutated acute myeloid leukemia (AML).
Explore the molecular mechanisms of resistance to tyrosine kinase-targeted therapy in non-small cell lung cancer and how cancer cells evolve to survive treatment.